Consider penicillin skin-testing to determine penicillin class sensitivity. The condition most commonly discussed is oral allergy syndrome (OAS), where reactions to certain proteins in pollen can also cause reactions to raw/fresh fruits, vegetables, nuts, seeds, and spices due to the existence of similar proteins in the foods and the pollen, most commonly profilin.
#Food cross reactivity chart skin#
Piperacillin-tazobactam – Similarly, allergic reaction specific to tazobactam is rare but possible. Skin test-positive food allergies seen in individuals who self-reported the clinical symptoms were tomato (6/10, 60), banana (2/5, 40), melon mix (2/3, 67), wheat (2/2, 100), peanuts (2/4, 50), pecan (1/2, 50), lima bean (1/1, 100), fish mix (1/3, 33), lobster (0/1, 0), crab (0/0, 0), and milk (0/2, 0). Consider penicillin skin-testing +/- amoxicillin challenge. Amoxicillin–clavulanate – patients who have a true IgE-mediated hypersensitivity to this drug combination may have an allergy to the clavulanate component, but not amoxicillin or other beta-lactam antibiotics.
This convenient table lists the possible pollen and plant food cross-reactivities. Those with reactions to ragweed might have symptoms when eating foods such as banana, cucumber, melon, and zucchini. In these patients, use clinical judgement and caution when prescribing any new antimicrobial. People with allergies to grasses may have a reaction to peaches, celery, tomatoes, melons (cantaloupe, watermelon and honeydew) and oranges. NB: Be aware that some patients may react to other β-lactams not because of cross-reactivity but because of their underlying predisposition to develop allergic reactions to multiple unrelated drugs (multiple drug allergy syndrome).
Avoid all β-lactam antibiotics if documented severe non-lgE-mediated reaction to penicillin: Food Families Foods can be grouped into families on the basis of similar molecular structures.
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